Name: TBP Mouse Monoclonal Description: Mouse Monoclonal Antibody to TBP Specificity: Human, Mouse , Rat Applications: ELISA, WB, IP Immunogen: TATA box binding protein Host: Mouse Clonality: Monoclonal Isotype: IgG2a Conjugate: Unconjugated Purity: Protein A+G purification (≥95% as determined by SDS-PAGE) Product Form: Liquid Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Uniprot information:
Gene Name TBP
Uniprot ID P20226
Targets:
Synonyms: GTF2D Antibody
GTF2D1 Antibody
HDL4 Antibody
MGC117320 Antibody
MGC126054 Antibody
MGC126055 Antibody
SCA17 Antibody
TATA binding factor Antibody
TATA binding protein TBP Antibody
TATA box binding protein Antibody
TATA box factor Antibody
TATA sequence binding protein Antibody
TATA sequence-binding protein Antibody
TATA-binding factor Antibody
TATA-box binding protein N-terminal domain Antibody
TATA-box factor Antibody
TATA-box-binding protein Antibody
TBP_HUMAN Antibody
TFIID Antibody
Transcription initiation factor TFIID TBP subunit Antibody
Research Areas:
Epigenetics and Nuclear Signaling → Transcription → Polymerase associated factors → Pol II Transcription → TFIIB
Epigenetics and Nuclear Signaling → Transcription → Polymerase associated factors → Pol II Transcription → TAFsIsotype/Loading Controls → Loading Controls → TBP - NuclearEpigenetics and Nuclear Signaling → Transcription → Preinitiation complexEpigenetics and Nuclear Signaling → ChIP'ing antibodies → ChIP'ing antibodiesPlease Note: TBP Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.