Name: | TBP Mouse Monoclonal |
Description: | Mouse Monoclonal Antibody to TBP |
Specificity: | Human, Mouse , Rat |
Applications: | ELISA, WB, IP |
Immunogen: | TATA box binding protein |
Host: | Mouse |
Clonality: | Monoclonal |
Isotype: | IgG2a |
Conjugate: | Unconjugated |
Purity: | Protein A+G purification (≥95% as determined by SDS-PAGE) |
Product Form: | Liquid |
Formulation: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
Background |
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. |
Uniprot information:
Gene Name | TBP |
Uniprot ID | P20226 |
Targets:
Synonyms: | GTF2D Antibody GTF2D1 Antibody HDL4 Antibody MGC117320 Antibody MGC126054 Antibody MGC126055 Antibody SCA17 Antibody TATA binding factor Antibody TATA binding protein TBP Antibody TATA box binding protein Antibody TATA box factor Antibody TATA sequence binding protein Antibody TATA sequence-binding protein Antibody TATA-binding factor Antibody TATA-box binding protein N-terminal domain Antibody TATA-box factor Antibody TATA-box-binding protein Antibody TBP_HUMAN Antibody TFIID Antibody Transcription initiation factor TFIID TBP subunit Antibody |
Research Areas:
Epigenetics and Nuclear Signaling → Transcription → Polymerase associated factors → Pol II Transcription → TFIIB
Epigenetics and Nuclear Signaling → Transcription → Polymerase associated factors → Pol II Transcription → TAFsIsotype/Loading Controls → Loading Controls → TBP - NuclearEpigenetics and Nuclear Signaling → Transcription → Preinitiation complexEpigenetics and Nuclear Signaling → ChIP'ing antibodies → ChIP'ing antibodies
Please Note: TBP Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.