Name: SSTR2 Rabbit Polyclonal
 
Description: Rabbit Polyclonal Antibody to SSTR2
Specificity: Human
Applications: ELISA, IHC
Immunogen: somatostatin receptor 2
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purity: Immunogen affinity purified (≥95% as determined by SDS-PAGE)
Product Form: Liquid
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

 

Background

Receptor for somatostatin-14 and-28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha-and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

 

Uniprot information:

Gene Name

SSTR2

Uniprot ID

P30874

 

Target:

Synonyms: Somatostatin Receptor 2 Antibody
Somatostatin receptor type 2 Antibody
SRIF-1 Antibody
SRIF1 Antibody
SS-2-R Antibody
SS2-R Antibody
SS2R Antibody
SSR2_HUMAN Antibody
SST2 Antibody

 

Research Areas:

Neuroscience Neurotransmitter Neuropeptides Hormones

Neuroscience Neurotransmission Receptors / Channels GPCR More GPCR
Neuroscience Neurology process Neuroendocrinology GH Regulation
Cancer Cancer Metabolism Metabolic signaling pathway Hormone biosynthesis
Metabolism Pathways and Processes Endocrine metabolism Hormone biosynthesis

 

Please Note: SSTR2 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.

 

 

SSTR2 Rabbit Polyclonal

SKU: MB08253
$330Price
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