Name:
SIRT3 Rabbit Polyclonal
 
Description:
Rabbit Polyclonal Antibody to SIRT3
Specificity:
Human, Mouse ,Rat
Applications:
ELISA, WB (Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:100; IF: 1:50 – 1:100)
Immunogen:
sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae), Calculated MW:44 kDa, 27 kDa
 
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Immunogen affinity purified (≥95% as determined by SDS-PAGE)
Product Form:
Liquid
Formulation:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Uniprot information:
Gene Name
SIRT3
Uniprot ID
Q9NTG7
 
Targets:
Synonyms:
hSIRT 3 Antibody
hSIRT3 Antibody
Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase Antibody
NAD dependent deacetylase sirtuin 3 mitochondrial Antibody
NAD-dependent protein deacetylase sirtuin-3, mitochondrial Antibody
Regulatory protein SIR2 homolog 3 Antibody
Silent mating type information regulation 2 S.cerevisiae homolog 3 Antibody
Sir 2 like 3 Antibody
SIR 2 like protein 3 Antibody
SIR 3 Antibody
SIR2 L3 Antibody
Sir2 like 3 Antibody
SIR2 like protein 3 Antibody
SIR2-like protein 3 Antibody
SIR2L3 Antibody
SIR3_HUMAN Antibody
SIRT 3 Antibody
SIRT3 Antibody
Sirtuin 3 Antibody
Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) Antibody
Sirtuin type 3 Antibody
Sirtuin3 Antibody
 
Research Areas:
Epigenetics and Nuclear Signaling → Chromatin Modifying Enzymes → Acetylation
Cell Biology → Cell Cycle → Cell Division → Other cell division antibodies
Epigenetics and Nuclear Signaling → Chromatin Modifying Enzymes → Acetylation → HDACs → Class III / Sir2 class
Cancer → Oncoproteins/suppressors → Tumor suppressors → Other
Cardiovascular → Heart → Cardiac metabolism
Metabolism → Types of disease → Obesity
 
Please Note: SIRT3 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.