Name:
SIRT2 Rabbit Polyclonal
 
Description:
Rabbit Polyclonal Antibody to SIRT2
Specificity:
Human, Mouse , Rat
Applications:
ELISA, WB, IHC, IP (Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IF: 1:10 – 1:100)
Immunogen:
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae), Synonyms:SIR2L, SIR2L2
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Immunogen affinity purified (≥95% as determined by SDS-PAGE)
Product Form:
Liquid
Formulation:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Uniprot information:
Gene Name
SIRT2
Uniprot ID
Q8IXJ6
Targets:
Synonyms:
FLJ35621 Antibody
FLJ37491 Antibody
NAD dependent deacetylase sirtuin 2 Antibody
NAD-dependent deacetylase sirtuin-2 Antibody
NAD-dependent protein deacetylase sirtuin-2 Antibody
Regulatory protein SIR2 homolog 2 Antibody
Silencing information regulator 2 like Antibody
Silent information regulator 2 Antibody
SIR2 Antibody
SIR2 like protein 2 Antibody
Sir2 related protein type 2 Antibody
SIR2, S. cerevisiae, homolog-loke 2 Antibody
SIR2-like protein 2 Antibody
SIR2L Antibody
SIR2L2 Antibody
SIRT2 Antibody
SIRT2_HUMAN Antibody
Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae) Antibody
Sirtuin 2 Antibody
Sirtuin type 2 Antibody
Research Areas:
Epigenetics and Nuclear Signaling → Chromatin Modifying Enzymes → Acetylation
Signal Transduction → Cytoskeleton / ECM → Cytoskeleton → Microtubules → Tubulin
Epigenetics and Nuclear Signaling → Chromatin Modifying Enzymes → Acetylation → HDACs → Class I
 
Please Note: SIRT2 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.