Name:
SIRT1 Rabbit Polyclonal
 
Description:
Rabbit Polyclonal Antibody to SIRT1
Specificity:
Human, Mouse ,Rat
Applications:
ELISA, IP, IHC, WB (Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IP: 1:50 – 1:100)
Immunogen:
sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), SynonymsSIR2L1, Calculated MW: 130 kDa
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Immunogen affinity purified
Product Form:
Liquid
Formulation:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
 
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
 
 
Uniprot information:
Gene Name
SIRT1
Uniprot ID
Q96EB6
 
Targets:
Synonyms:
75SirT1 Antibody
hSIR2 Antibody
hSIRT1 Antibody
HST2, S. cerevisiae, homolog of Antibody
NAD dependent deacetylase sirtuin 1 Antibody
NAD dependent protein deacetylase sirtuin 1 Antibody
OTTHUMP00000198111 Antibody
OTTHUMP00000198112 Antibody
Regulatory protein SIR2 homolog 1 Antibody
SIR1_HUMAN Antibody
SIR2 Antibody
SIR2 like 1 Antibody
SIR2 like protein 1 Antibody
SIR2, S.cerevisiae, homolog-like 1 Antibody
SIR2-like protein 1 Antibody
SIR2ALPHA Antibody
SIR2L1 Antibody
SIRT1 Antibody
SirtT1 75 kDa fragment Antibody
Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) Antibody
Sirtuin 1 Antibody
Sirtuin type 1 Antibody
 
Research Areas:
Cell Biology → Apoptosis → Intracellular → p53 Pathway
Epigenetics and Nuclear Signaling → Chromatin Modifying Enzymes → Acetylation
Microbiology → Interspecies Interaction → Host Virus Interaction
Tags & Cell Markers → Subcellular Markers → Nucleus → Other Nuclear Bodies
Epigenetics and Nuclear Signaling → Chromatin Modifying Enzymes → Acetylation → HDACs → Class III / Sir2 class
Metabolism → Types of disease → Obesity
 
Please Note: SIRT1 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.