Name: SIRT1 Rabbit Polyclonal
 
Description: Rabbit Polyclonal Antibody to SIRT1
Specificity: Human, Mouse ,Rat
Applications: ELISA, IP, IHC, WB (Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IP: 1:50 – 1:100)
Immunogen: sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), SynonymsSIR2L1, Calculated MW: 130 kDa
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purity: Immunogen affinity purified
Product Form: Liquid
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

 

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

 

 

Uniprot information:

Gene Name

SIRT1

Uniprot ID

Q96EB6

 

Targets:

Synonyms:
  • 75SirT1 Antibody
  • hSIR2 Antibody
  • hSIRT1 Antibody
  • HST2, S. cerevisiae, homolog of Antibody
  • NAD dependent deacetylase sirtuin 1 Antibody
  • NAD dependent protein deacetylase sirtuin 1 Antibody
  • OTTHUMP00000198111 Antibody
  • OTTHUMP00000198112 Antibody
  • Regulatory protein SIR2 homolog 1 Antibody
  • SIR1_HUMAN Antibody
  • SIR2 Antibody
  • SIR2 like 1 Antibody
  • SIR2 like protein 1 Antibody
  • SIR2, S.cerevisiae, homolog-like 1 Antibody
  • SIR2-like protein 1 Antibody
  • SIR2ALPHA Antibody
  • SIR2L1 Antibody
  • SIRT1 Antibody
  • SirtT1 75 kDa fragment Antibody
  • Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) Antibody
  • Sirtuin 1 Antibody
  • Sirtuin type 1 Antibody

 

Research Areas:

Cell Biology Apoptosis Intracellular p53 Pathway

Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes Acetylation
Microbiology Interspecies Interaction Host Virus Interaction
Tags & Cell Markers Subcellular Markers Nucleus Other Nuclear Bodies
Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes Acetylation HDACs Class III / Sir2 class
Metabolism Types of disease Obesity
 

Please Note: SIRT1 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.

 

 

 

 

SIRT1 Rabbit Polyclonal

SKU: MB07877
$310Price
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