Name: | NXN Rabbit Polyclonal |
Description: | Rabbit Polyclonal Antibody to NXN |
Specificity: | Human, Mouse ,Rat |
Applications: | ELISA, WB, IHC, IF, IP |
Immunogen: | nucleoredoxin (Calculated MW: 48 kDa) |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Unconjugated |
Purity: | Immunogen affinity purified (≥95% as determined by SDS-PAGE) |
Product Form: | Liquid |
Formulation: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
Background |
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A(PP2A)(By similarity). |
Uniprot information:
Gene Name | NXN |
Uniprot ID | Q6DKJ4 |
Target:
Synonyms: | FLJ12614 Antibody NRX Antibody Nucleoredoxin Antibody nucleoredoxin 1 Antibody NXN_HUMAN Antibody OTTHUMP00000115356 Antibody TRG 4 Antibody |
Research Areas:
Signal Transduction → Protein Phosphorylation → Ser / Thr Phosphatases
Stem Cells → Signaling Pathways → Wnt → CytoplasmicStem Cells → Signaling Pathways → Wnt → Nuclear
Please Note: NXN Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.