Name: NXN Rabbit Polyclonal Description: Rabbit Polyclonal Antibody to NXN Specificity: Human, Mouse ,Rat Applications: ELISA, WB, IHC, IF, IP Immunogen: nucleoredoxin (Calculated MW: 48 kDa) Host: Rabbit Clonality: Polyclonal Isotype: IgG Conjugate: Unconjugated Purity: Immunogen affinity purified (≥95% as determined by SDS-PAGE) Product Form: Liquid Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A(PP2A)(By similarity).
Synonyms: FLJ12614 Antibody
nucleoredoxin 1 Antibody
TRG 4 Antibody
Signal Transduction → Protein Phosphorylation → Ser / Thr PhosphatasesStem Cells → Signaling Pathways → Wnt → CytoplasmicStem Cells → Signaling Pathways → Wnt → Nuclear
Please Note: NXN Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.