Name:
NXN Rabbit Polyclonal
 
Description:
Rabbit Polyclonal Antibody to NXN
Specificity:
Human, Mouse ,Rat
Applications:
ELISA, WB, IHC, IF, IP
Immunogen:
nucleoredoxin (Calculated MW: 48 kDa)
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Immunogen affinity purified (≥95% as determined by SDS-PAGE)
Product Form:
Liquid
Formulation:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
 
Background
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A(PP2A)(By similarity).
 
Uniprot information:
Gene Name
NXN
Uniprot ID
Q6DKJ4
 
Target:
Synonyms:
FLJ12614 Antibody
NRX Antibody
Nucleoredoxin Antibody
nucleoredoxin 1 Antibody
NXN_HUMAN Antibody
OTTHUMP00000115356 Antibody
TRG 4 Antibody
 
Research Areas:
Signal Transduction → Protein Phosphorylation → Ser / Thr Phosphatases
Stem Cells → Signaling Pathways → Wnt → Cytoplasmic
Stem Cells → Signaling Pathways → Wnt → Nuclear
 
Please Note: NXN Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.