Name: N-cadherin Mouse Monoclonal Description: Mouse Monoclonal Antibody to N-cadherin Specificity: Human, Pig, Mouse , Rat Applications: ELISA, IHC, WB (Recommended dilutionWB: 1:1000-1:10000; IHC: 1:20-1:200) Immunogen: cadherin 2, type 1, N-cadherin (neuronal) (Calculated MW:130 kDa ) Host: Mouse Clonality: Monoclonal Isotype: IgG2a Conjugate: Unconjugated Purity: Protein A+G purification (≥95% as determined by SDS-PAGE) Product Form: Liquid Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).
Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin
Please Note: N-cadherin Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.