Name: N-cadherin Mouse Monoclonal
 
Description: Mouse Monoclonal Antibody to N-cadherin
Specificity: Human, Pig, Mouse , Rat
Applications: ELISA, IHC, WB (Recommended dilutionWB: 1:1000-1:10000; IHC: 1:20-1:200)
Immunogen: cadherin 2, type 1, N-cadherin (neuronal) (Calculated MW:130 kDa )
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Conjugate: Unconjugated
Purity: Protein A+G purification (≥95% as determined by SDS-PAGE)
Product Form: Liquid
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

 

Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).

 

Uniprot information:

Gene Name

N-cadherin

Uniprot ID

P19022

 

Targets:

Synonyms

Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin

 

Research Areas:

 

Please Note: N-cadherin Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.

 

 

 

 

N-cadherin Mouse Monoclonal

SKU: MB005571
$270Price
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