Name: | IL23A Mouse Monoclonal |
Description: | Mouse Monoclonal Antibody to IL23A |
Specificity: | Human |
Applications: | ELISA, WB, IHC |
Immunogen: | interleukin 23, alpha subunit p19 (Calculated MW:21 kDa) |
Host: | Mouse |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Conjugate: | Unconjugated |
Purity: | Protein A+G purification (≥95% as determined by SDS-PAGE) |
Product Form: | Liquid |
Formulation: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
Background |
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Uniprot information:
Gene Name | IL23A |
Uniprot ID | Q9NPF7 |
Target:
Synonyms: | IL 23 Antibody IL 23 A Antibody IL 23 subunit alpha Antibody IL 23A Antibody IL 23p19 Antibody IL-23 subunit alpha Antibody IL-23-A Antibody IL-23p19 Antibody IL12B Antibody IL23 Antibody IL23A_HUMAN Antibody IL23P19 Antibody interleukin 12B Antibody Interleukin 23 alpha subunit p19 Antibody Interleukin 23 p19 subunit Antibody interleukin 23 subunit alpha Antibody interleukin 23 subunit p19 Antibody interleukin six, G CSF related factor Antibody Interleukin-23 subunit alpha Antibody Interleukin-23 subunit p19 Antibody JKA3 induced upon T cell activation Antibody MGC79388 Antibody P19 Antibody SGRF Antibody |
Research Areas:
Immunology → Innate Immunity → Cytokines → Interleukins
Microbiology → Interspecies Interaction → Host Virus InteractionCancer → Tumor immunology → Cytokines → Interleukins
Please Note: IL23A Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.