Name: IL1R2 Mouse Monoclonal Description: Mouse Monoclonal Antibody to IL1R2 Specificity: Human, Mouse Applications: ELISA, WB, IF Immunogen: interleukin 1 receptor, type II Host: Mouse Clonality: Monoclonal Isotype: IgG1 Conjugate: Unconjugated Purity: Protein A+G purification (≥95% as determined by SDS-PAGE) Product Form: Liquid Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Uniprot information:
Gene Name IL1R2
Uniprot ID P27930
Target:
Synonyms: IL1 Receptor II Antibody
Antigen CDw121b Antibody
CD121 Antibody
CD121 antigen-like family member B Antibody
CD121b Antibody
CD121B Antigen Antibody
CDw121b Antibody
IL 1 type II receptor Antibody
IL-1R-2 Antibody
IL-1R-beta Antibody
IL-1R2 Antibody
IL-1RT-2 Antibody
IL-1RT2 Antibody
IL1 Receptor II Antibody
IL1R Beta Antibody
Il1r-2 Antibody
IL1R2c Antibody
IL1R2_HUMAN Antibody
IL1RB Antibody
Interleukin 1 receptor type II variant 3 Antibody
Interleukin 1 receptor, beta, type II Antibody
Interleukin 1 receptor, type II Antibody
Interleukin-1 receptor beta Antibody
Interleukin-1 receptor type 2 Antibody
Research Areas:
Immunology → Innate Immunity → Cytokines → Interleukins
Stem Cells → Hematopoietic Progenitors → Lymphoid → B Lymphocytic LineageCardiovascular → Angiogenesis → Endothelial Cell Markers
Please Note: IL1R2 Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.