Name: | IL1R2 Mouse Monoclonal |
Description: | Mouse Monoclonal Antibody to IL1R2 |
Specificity: | Human, Mouse |
Applications: | ELISA, WB, IF |
Immunogen: | interleukin 1 receptor, type II |
Host: | Mouse |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Conjugate: | Unconjugated |
Purity: | Protein A+G purification (≥95% as determined by SDS-PAGE) |
Product Form: | Liquid |
Formulation: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
Background |
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. |
Uniprot information:
Gene Name | IL1R2 |
Uniprot ID | P27930 |
Target:
Synonyms: | IL1 Receptor II Antibody Antigen CDw121b Antibody CD121 Antibody CD121 antigen-like family member B Antibody CD121b Antibody CD121B Antigen Antibody CDw121b Antibody IL 1 type II receptor Antibody IL-1R-2 Antibody IL-1R-beta Antibody IL-1R2 Antibody IL-1RT-2 Antibody IL-1RT2 Antibody IL1 Receptor II Antibody IL1R Beta Antibody Il1r-2 Antibody IL1R2c Antibody IL1R2_HUMAN Antibody IL1RB Antibody Interleukin 1 receptor type II variant 3 Antibody Interleukin 1 receptor, beta, type II Antibody Interleukin 1 receptor, type II Antibody Interleukin-1 receptor beta Antibody Interleukin-1 receptor type 2 Antibody |
Research Areas:
Immunology → Innate Immunity → Cytokines → Interleukins
Stem Cells → Hematopoietic Progenitors → Lymphoid → B Lymphocytic LineageCardiovascular → Angiogenesis → Endothelial Cell Markers
Please Note: IL1R2 Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.