Name: | IL-6 Mouse Monoclonal |
Description: | Mouse Monoclonal Antibody to IL-6 |
Specificity: | Human |
Applications: | ELISA, IHC, WB (Recommended dilutionWB: 1:500-1:5000；IHC: 1:20-1:200) |
Immunogen: | interleukin 6 (interferon, beta 2) (Calculated MW:30kDa) |
Host: | Mouse |
Clonality: | Monoclonal |
Isotype: | IgG2a |
Conjugate: | Unconjugated |
Purity: | Protein A+G purification |
Product Form: | Liquid |
Formulation: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
Background |
Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. |
Uniprot information:
Gene Name | IL-6 |
Uniprot ID | P05231 |
Targets:
Synonyms: | Interleukin BSF 2 Antibody B cell differentiation factor Antibody B cell stimulatory factor 2 Antibody B-cell stimulatory factor 2 Antibody BSF 2 Antibody BSF-2 Antibody BSF2 Antibody CDF Antibody CTL differentiation factor Antibody Hepatocyte stimulatory factor Antibody HGF Antibody HSF Antibody Hybridoma growth factor Antibody Hybridoma growth factor Interferon beta-2 Antibody IFN-beta-2 Antibody IFNB2 Antibody IL 6 Antibody IL6 Antibody IL6_HUMAN Antibody Interferon beta 2 Antibody Interferon beta-2 Antibody Interleukin 6 Antibody Interleukin 6 (interferon beta 2) Antibody Interleukin BSF 2 Antibody Interleukin-6 Antibody |
Research Areas:
Immunology → Innate Immunity → Cytokines → Interleukins
Neuroscience → Neurology process → MetabolismCancer → Invasion/microenvironment → Angiogenesis → Angiogenic growth factorsCancer → Tumor immunology → Cytokines → InterleukinsMetabolism → Types of disease → ObesityMetabolism → Types of disease → CancerMetabolism → Types of disease → Metabolic disorders
Please Note: IL-6 Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.