Name:
IL-6 Mouse Monoclonal
 
Description:
Mouse Monoclonal Antibody to IL-6
Specificity:
Human
Applications:
ELISA, IHC, WB (Recommended dilutionWB: 1:500-1:5000；IHC: 1:20-1:200)
Immunogen:
interleukin 6 (interferon, beta 2) (Calculated MW:30kDa)
Host:
Mouse
Clonality:
Monoclonal
Isotype:
IgG2a
Conjugate:
Unconjugated
Purity:
Protein A+G purification
Product Form:
Liquid
Formulation:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
 
Background
Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
 
Uniprot information:
Gene Name
IL-6
Uniprot ID
P05231
 
Targets:
Synonyms:
Interleukin BSF 2 Antibody
B cell differentiation factor Antibody
B cell stimulatory factor 2 Antibody
B-cell stimulatory factor 2 Antibody
BSF 2 Antibody
BSF-2 Antibody
BSF2 Antibody
CDF Antibody
CTL differentiation factor Antibody
Hepatocyte stimulatory factor Antibody
HGF Antibody
HSF Antibody
Hybridoma growth factor Antibody
Hybridoma growth factor Interferon beta-2 Antibody
IFN-beta-2 Antibody
IFNB2 Antibody
IL 6 Antibody
IL6 Antibody
IL6_HUMAN Antibody
Interferon beta 2 Antibody
Interferon beta-2 Antibody
Interleukin 6 Antibody
Interleukin 6 (interferon beta 2) Antibody
Interleukin BSF 2 Antibody
Interleukin-6 Antibody
 
Research Areas:
Immunology → Innate Immunity → Cytokines → Interleukins
Neuroscience → Neurology process → Metabolism
Cancer → Invasion/microenvironment → Angiogenesis → Angiogenic growth factors
Cancer → Tumor immunology → Cytokines → Interleukins
Metabolism → Types of disease → Obesity
Metabolism → Types of disease → Cancer
Metabolism → Types of disease → Metabolic disorders
 
Please Note: IL-6 Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.