Name: EXO1 Rabbit Polyclonal Description: Rabbit Polyclonal Antibody to EXO1 Specificity: Human Applications: ELISA, WB Immunogen: exonuclease 1 Host: Rabbit Clonality: Polyclonal Isotype: IgG Conjugate: Unconjugated Purity: Immunogen affinity purified Product Form: Liquid Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background 5′->3′ double-stranded DNA exonuclease which may also possess a cryptic 3′->5′ double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch- containing DNA tracts directed by strand breaks located either 5′ or 3′ to the mismatch. Also exhibits endonuclease activity against 5′-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5′-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Uniprot information:
Gene Name EXO1
Uniprot ID Q9UQ84
Target:
Synonyms: Beta D glucan exohydrolase isoenzyme ExoI Antibody
EXO1_HUMAN Antibody
ExoI Antibody
Exonuclease 1 Antibody
Exonuclease I Antibody
Exonuclease1 Antibody
HEX1 Antibody
hExo I Antibody
hExo1 Antibody
hExoI Antibody
Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 Antibody
Research Areas:
Signal Transduction → Metabolism → Energy Metabolism
Cell Biology → Other Antibodies → Plant related targetsMetabolism → Pathways and Processes → Metabolic signaling pathways → Energy transfer pathways → Energy MetabolismMetabolism → Types of disease → Cancer
Please Note: EXO1 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.