Name: | EXO1 Rabbit Polyclonal |
Description: | Rabbit Polyclonal Antibody to EXO1 |
Specificity: | Human |
Applications: | ELISA, WB |
Immunogen: | exonuclease 1 |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Unconjugated |
Purity: | Immunogen affinity purified |
Product Form: | Liquid |
Formulation: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
Background |
5′->3′ double-stranded DNA exonuclease which may also possess a cryptic 3′->5′ double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch- containing DNA tracts directed by strand breaks located either 5′ or 3′ to the mismatch. Also exhibits endonuclease activity against 5′-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5′-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis. |
Uniprot information:
Gene Name | EXO1 |
Uniprot ID | Q9UQ84 |
Target:
Synonyms: | Beta D glucan exohydrolase isoenzyme ExoI Antibody EXO1_HUMAN Antibody ExoI Antibody Exonuclease 1 Antibody Exonuclease I Antibody Exonuclease1 Antibody HEX1 Antibody hExo I Antibody hExo1 Antibody hExoI Antibody Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 Antibody |
Research Areas:
Signal Transduction → Metabolism → Energy Metabolism
Cell Biology → Other Antibodies → Plant related targetsMetabolism → Pathways and Processes → Metabolic signaling pathways → Energy transfer pathways → Energy MetabolismMetabolism → Types of disease → Cancer
Please Note: EXO1 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.