Name: ECD Rabbit Polyclonal
 
Description: Rabbit Polyclonal Antibody to ECD
Specificity: Human, Mouse
Applications: ELISA, WB, IF, IP
Immunogen: ecdysoneless homolog (Drosophila)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purity: Immunogen affinity purified
Product Form: Liquid
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

 

Background

Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212).

 

Uniprot information:

Gene Name

ECD

Uniprot ID

O95905

 

Target:

Synonyms: Ecdysoneless homolog Antibody
ECD_HUMAN Antibody
hSGT1 Antibody
Human suppressor of GCR two Antibody
Protein ecdysoneless homolog Antibody
SGT 1 Antibody
SGT1 Antibody
SGT1 protein Antibody
Suppressor of GCR2 Antibody

 

Research Areas:

Signal Transduction Metabolism Energy Metabolism

Epigenetics and Nuclear Signaling Transcription Other factors
Metabolism Pathways and Processes Metabolic signaling pathways Energy transfer pathways Energy Metabolism
Metabolism Types of disease Cancer

 

Please Note: ECD Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.

 

ECD Rabbit Polyclonal

SKU: MB02619
$310Price
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