Name: DDR1 Rabbit Polyclonal
 
Description: Rabbit Polyclonal Antibody to DDR1
Specificity: Human, Mouse ,Rat
Applications: ELISA, IHC
Immunogen: discoidin domain receptor tyrosine kinase 1
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purity: Immunogen affinity purified
Product Form: Liquid
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

 

Background

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.

 

Uniprot information:

Gene Name

DDR1

Uniprot ID

Q08345

 

Target:

Synonyms

CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE

 

Research Areas:

 

Please Note: DDR1 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.

 

DDR1 Rabbit Polyclonal

SKU: MB02291
$270Price
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