Name: CRHR1 Rabbit Polyclonal Description: Rabbit Polyclonal Antibody to CRHR1 Specificity: Human Applications: ELISA, WB Immunogen: corticotropin releasing hormone receptor 1 Host: Rabbit Clonality: Polyclonal Isotype: IgG Conjugate: Unconjugated Purity: Immunogen affinity purified Product Form: Liquid Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
G-protein coupled receptor for CRH (corticotropin- releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
Synonyms: Corticotropin releasing factor type 1 receptor Antibody
corticotropin releasing hormone receptor 1 Antibody
Corticotropin-releasing factor receptor 1 Antibody
Corticotropin-releasing hormone receptor 1 Antibody
CRF R Antibody
crf receptor 1 Antibody
crf receptor type 1 Antibody
crf type 1 Antibody
Signal Transduction → Signaling Pathway → Nuclear Signaling → Nuclear Hormone Receptors → CorticoidNeuroscience → Neurology process → MetabolismNeuroscience → Endocrine system → Hypothalamic pituitary adrenal axisMetabolism → Types of disease → ObesityMetabolism → Types of disease → Cancer
Please Note: CRHR1 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.