Name: | CRHR1 Rabbit Polyclonal |
Description: | Rabbit Polyclonal Antibody to CRHR1 |
Specificity: | Human |
Applications: | ELISA, WB |
Immunogen: | corticotropin releasing hormone receptor 1 |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Unconjugated |
Purity: | Immunogen affinity purified |
Product Form: | Liquid |
Formulation: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
Background |
G-protein coupled receptor for CRH (corticotropin- releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli. |
Uniprot information:
Gene Name | CRHR1 |
Uniprot ID | P34998 |
Target:
Synonyms: | Corticotropin releasing factor type 1 receptor Antibody corticotropin releasing hormone receptor 1 Antibody Corticotropin-releasing factor receptor 1 Antibody Corticotropin-releasing hormone receptor 1 Antibody CRF R Antibody crf receptor 1 Antibody crf receptor type 1 Antibody crf type 1 Antibody CRF-R Antibody CRF-R-1 Antibody CRF-R1 Antibody CRF1 Antibody CRFR Antibody CRFR-1 Antibody CRFR1 Antibody CRFR1_HUMAN Antibody CRH-R-1 Antibody CRH-R1 Antibody CRH-R1h Antibody CRHR Antibody CRHR1f Antibody CRHR1L Antibody |
Research Areas:
Signal Transduction → Signaling Pathway → Nuclear Signaling → Nuclear Hormone Receptors → Corticoid
Neuroscience → Neurology process → MetabolismNeuroscience → Endocrine system → Hypothalamic pituitary adrenal axisMetabolism → Types of disease → ObesityMetabolism → Types of disease → Cancer
Please Note: CRHR1 Rabbit Polyclonal is for research use only. It is not intended for diagnostic or therapeutic use.