Name: Caspase 8 Mouse Monoclonal
 
Description: Mouse Monoclonal Antibody to Caspase 8
Specificity: Human
Applications: ELISA, IHC, WB
Immunogen: caspase 8, apoptosis-related cysteine peptidase (Calculated MW: 50-55 kDa, 25-32 kDa)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Conjugate: Unconjugated
Purity: Protein A+G purification (≥95% as determined by SDS-PAGE)
Product Form: Liquid
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Recommended dilution

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:50-1:500

 

Background

Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. 66093-1-AP can recognize pro-and cleaved-caspase 8.

 

Uniprot information:

Gene Name

Caspase 8

Uniprot ID

Q14790

 

Target:

Synonyms: ALPS2B Antibody
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein Antibody
Apoptotic cysteine protease Antibody
Apoptotic protease Mch-5 Antibody
Apoptotic protease Mch5 Antibody
CAP4 Antibody
CASP-8 Antibody
CASP8 Antibody
CASP8_HUMAN Antibody
Caspase 8 apoptosis related cysteine peptidase Antibody
Caspase-8 Antibody
Caspase-8 subunit p10 Antibody
CED 3 Antibody
FADD Like ICE Antibody
FADD-homologous ICE/CED-3-like protease Antibody
FADD-like ICE Antibody
FLICE Antibody
FLJ17672 Antibody
ICE-like apoptotic protease 5 Antibody
MACH Antibody
MACH alpha 1/2/3 protein Antibody
MACH beta 1/2/3/4 protein Antibody
MCH5 Antibody
MGC78473 Antibody
MORT1 associated ced 3 homolog Antibody
MORT1-associated CED-3 homolog Antibody
OTTHUMP00000163717 Antibody
OTTHUMP00000163720 Antibody
OTTHUMP00000163724 Antibody
OTTHUMP00000163725 Antibody
OTTHUMP00000165062 Antibody
OTTHUMP00000165063 Antibody
OTTHUMP00000165064 Antibody
OTTHUMP00000206552 Antibody
OTTHUMP00000206582 Antibody

 

Research Areas:

 

Please Note: Caspase 8 Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.

 

 

 

 

Caspase 8 Mouse Monoclonal

SKU: MB01294
$270Price
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